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Objective
The prevalence of obesity has created a plethora of questionnaires characterizing psychological aspects of eating behavior, such as reward‐related eating (RRE). The Reward‐based Eating Drive questionnaires (RED‐9, RED‐13) broadly and deeply assess the RRE construct. However, large‐sample research designs require shorter questionnaires that capture RRE quickly and precisely. This study sought...
Objective
This randomized trial tested whether a behavioral intervention with meal replacements in pregnancy could increase the proportion of women who returned to prepregnancy weight and reduce postpartum weight retention by 12 months after delivery.
Methods
Women (N = 264; 13.7 weeks’ gestation) with overweight or obesity were randomly assigned to usual care or intervention. The intervention...
Objective
This study aimed to describe beverages purchased in restaurants among a nationally representative sample of US households.
Methods
Data were obtained from the US Department of Agriculture National Household Food Acquisition and Purchase Survey, 2012 to 2013. Survey‐weighted multiple regressions assessed correlates of purchasing a sugar‐sweetened beverage (SSB), purchasing a low‐calorie...
Objective
This study examined how parental general monitoring (PGM), which refers to parental awareness of adolescents’ activities in various domains, is associated with adolescents’ weight status and related behaviors and whether these relationships differ among racial/ethnic groups.
Methods
Data are from 4,088 Black, Latino, and White youth assessed in seventh grade (mean age = 13.06). BMI percentile...
Objective
Weight recidivism following Roux‐en‐Y gastric bypass (RYGB) is common and is associated with recurrence of comorbidities. Studies with long‐term follow‐up of recidivism quantified by weight regain (WR) are lacking. A retrospective review of all RYGB at our center from 2004 to 2015 was performed to examine the effects of race and type 2 diabetes on WR following RYGB.
Methods
Multivariable...
Objective
The aim of this study was to estimate frequency and prevalence of obesity, metabolic syndrome, and diabetes mellitus in US adults.
Methods
Data were extracted from the National Health and Nutrition Examination Survey (NHANES; 2003‐2004 to 2013‐2014) (n = 32,188). The frequency and prevalence of diabetes mellitus, metabolic syndrome, obesity (BMI ≥ 30 kg/m2), and abdominal obesity were...
Objective
Atrial fibrillation (AF) is the most common arrhythmia and has been described as a global epidemic. Although AF is associated with both obesity and its metabolic consequences, little is known about the association between metabolically healthy obesity and AF.
Methods
In a population‐based study, 47,870 adults were followed for incident AF from 2006 to 2008 until 2015. Participants were...
Objective
A growing body of evidence suggests that obesity could result from alterations in reward processing. In rodent models, chronic exposure to an obesogenic diet leads to blunted dopamine signaling and related incentive responding. This study aimed to determine which reward‐related behavioral dimensions are actually impacted by obesogenic diet exposure.
Methods
Mice were chronically exposed...
Objective
This study quantified the obesity‐stroke relationship by appropriately adjusting for time‐varying confounders using G‐estimation.
Methods
A total of 13,975 participants in the Atherosclerosis Risk in Communities (ARIC) study were included. General obesity (GOB) was defined as BMI ≥ 30 kg/m2; abdominal obesity (AOB) was defined as waist circumference ≥ 102 cm in men and ≥ 88 cm in...
A growing number of youth suffer from obesity and in particular severe obesity for which intensive lifestyle intervention does not adequately reduce excess adiposity. A treatment gap exists wherein effective treatment options for an adolescent with severe obesity include intensive lifestyle modification or metabolic and bariatric surgery while the application of obesity pharmacotherapy remains largely...
Objective
Exosomal microRNAs (miRNAs) are potential biomarkers for obesity, in which they regulate biological processes. Bariatric surgery has health benefits for patients with obesity; however, the mechanisms of these benefits are not clear. This study attempted to identify the exosomal miRNA signature associated with obesity and how it changed after bariatric surgery.
Methods
Healthy volunteers...
Objective
This study investigated the influence of birth weight on the risk of pregnancy complications, including preeclampsia (PE), gestational hypertension (GH), small for gestational age (SGA) pregnancy, spontaneous preterm birth, and gestational diabetes mellitus (GDM), and assessed the effect of early pregnancy BMI on this relationship.
Methods
A total of 5,336 nulliparous women from the SCreening...
Objective
This study aims to assess the efficacy and safety of Gelesis100, a novel, nonsystemic, superabsorbent hydrogel to treat overweight or obesity.
Methods
The Gelesis Loss Of Weight (GLOW) study was a 24‐week, multicenter, randomized, double‐blind, placebo‐controlled study in patients with BMI ≥ 27 and ≤ 40 kg/m2 and fasting plasma glucose ≥ 90 and ≤ 145 mg/dL. The co‐primary end points...
Objective
Treating pediatric severe obesity is challenging because of the complex biological, behavioral, and environmental factors that underpin the disease. The multifactorial etiology of obesity combined with the physiologic complexity of the energy regulatory system contributes to treatment variability. The goal of this secondary analysis of pooled data was to describe the degree of individual...
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